A night of wholesale team changes for the 11 Premier League sides in action produced one notable upset with top flight Stoke City losing 2-0 at second-tier Bristol City.
Images from Sunday's English Premier League matches.
Tottenham Hotspur missed the chance to move up to provisional fourth place in the Premier League after relegation-threatened Newcastle United held them to a 2-2 draw with a late equaliser from substitute Joe Willock at St James' Park on Sunday. Images from EPL matches played on Sunday.
Images from Sunday's action in the Premier League.
Liverpool face Spurs in the game of the weekend, a day after title rivals Manchester City travel to struggling Fulham.
Liverpool head to United with widest gulf in years
Bernardo Silva has made an encouraging start to the Premier League campaign and the Manchester City midfielder said that feeling more settled at his second season with the champions was a key factor in his performances.
IMAGES from Premier League matches played on Saturday.
Manchester City needed a second-half penalty from striker Erling Haaland to break the resistance of a dogged Crystal Palace.
Romelu Lukaku extended his impressive FA Cup scoring record by netting twice in Manchester United's 2-0 win at Huddersfield Town to earn Jose Mourinho's side a quarter-final tie at home to Brighton & Hove Albion.
Ayew strikes as Palace hold Southampton to 2-2 draw
Arsenal's best chance to equalise came from a Granit Xhaka free kick which looked destined for the top corner until the Gunner's former keeper Emiliano Martinez at full stretch pushed it around the post with a fingertip save.
Manchester City's Sergio Aguero had said a number of players would be fearful of resuming the season amid the virus outbreak with more than 4.02 million people infected globally and over 276,000 dead.
Under-fire Jose Mourinho had been on the verge of delivering the perfect response to his critics on Saturday with Manchester United closing in on a second consecutive comeback win, at the home of his old club Chelsea to boot.
Liverpool manager Brendan Rodgers was an immensely proud but competitive dad at Anfield on Sunday as his Premier League side overcame the FA Cup challenge of his son's third tier Oldham Athletic.
Spain are still favourites to finish top of Group E above Sweden, Poland and Slovakia but, after struggling to break down conservative sides such as Georgia and Greece in March, they know coming first will not be a procession.
News of all that's transpired on and off the football field
Spurs striker Bergwijn is major casualty as Netherlands trim squad
Leicester City's veteran striker Jamie Vardy came off the bench to break his long scoring drought and earn his side a 1-1 draw with a late equaliser
Chelsea moved into the Premier League's top four as Mason Mount's superb first-half goal earned them a 1-0 win at champions Liverpool who suffered a club-record fifth straight home league defeat on Thursday.
Chelsea have topped the spending list with Manchester United not far behind, but West Ham United's business epitomises the TV riches which give all Premier League clubs spending power that only the elite teams in Spain or Germany can dream of.
Talking points from this weekend's Premier League action as top two Manchester City and Liverpool both won with City remaining a point clear with two games remaining.
A preview of the line-up action in the English Premier League
Valencia sign Kondogbia on loan from Inter
Manchester City host Tottenham Hotspur on Saturday on the back of a record 15 successive English Premier League wins, and on the basis of their visitors' recent away form, a 16th victory appears to be the likely outcome.
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Following is a match by match look at the English Premier League's weekend fixtures:
Liverpool cranked up the pressure on West Ham United manager Slaven Bilic with a 4-1 victory at the London Stadium, while Burnley's remarkable start to the Premier League season continued thanks to a 1-0 victory at Southampton on Saturday.
Manchester City and Everton players took to the field wearing Ukrainian flags before their Premier League game on Saturday while there were anti-war messages at stadiums elsewhere following Russia's invasion of Ukraine.
News of all that's transpired on and off the football field
Images from the Premier League matches played on Saturday.
News of all that transpired on and off the football field.
Luton pulled one back on the half-hour mark when Chelsea keeper Kepa Arrizabalaga failed to keep out Jordan Clark's low effort which squeezed between his hand and leg into the net.
Champions Manchester City will expect to get back to winning ways at home to Newcastle United in a match which pits Pep Guardiola against his fellow Spaniard Rafa Benitez.
Ajax wary of attacking Napoli.
IMAGES from the English Premier League matches played on Saturday.
Leicester will remain second overnight with Everton, level on points with them, not playing later on Monday after their home match against Manchester City was postponed following more positive COVID-19 cases at City.
Pep Guardiola hailed Sergio Aguero's 'unique' skill of sniffing out chances in front of goal, and David Silva's ability to ghost past defenders
Frank Lampard and Edin Dzeko scored twice as holders Manchester City sailed into the English League Cup fourth round with a crushing 7-0 win over Sheffield Wednesday and Chelsea beat Bolton Wanderers 2-1 on Wednesday.
EPL's 'Project Restart' envisages a return to play in June at neutral venues, once given the green light from the government, but players are worried about transmission when sharing the pitch with others in a contact sport.